What Are the Side Effects of Clindamycin For Dogs?

Clindamycin is a broad spectrum antibiotic designed to treat multiple forms of infections in dogs. Generally given in tablet form or as liquid doses for best results. Due to its bitter taste and potential to cause drooling issues, it should always be administered along with food.

When giving pills to your dog, always do so with water so as to prevent any lodgement in their esophagus and subsequent ulceration. Also follow all instructions provided by your veterinarian.

Allergic Reactions

While clindamycin can be very effective against many bacterial infections in dogs, it may also trigger allergic reactions in certain dogs. Dogs that have experienced previous skin allergies (eczema or hives) are more prone to adverse side effects from this antibiotic medication and should only take it under close veterinary supervision. It should also be used cautiously by those suffering from liver or kidney disease since taking too much could increase liver enzymes levels leading to elevated levels of bile acids entering their bloodstream causing damage to organs affecting organ function affecting them organ health causing further organ harm

Clindamycin’s most frequent adverse side effects are digestive related, such as stomach pain, nausea and watery or bloody diarrhea in your pet. These symptoms often develop shortly after starting this medicine and should disappear once their bodies have had time to eliminate the excess medications from their system. It’s recommended to administer their dosage with food to decrease chances of unpleasant reactions as this helps the drug absorb faster into their systems.

Long-term use of clindamycin may lead to the growth of antibiotic-resistant bacteria in your pet’s digestive system, making future infections harder to treat. Please take the necessary steps in accordance with your veterinarian’s recommendation to administer this antibiotic at its full dose and duration.

This medication should usually be given orally in capsule or liquid form; however, injection may also be possible depending on its formulation. Your veterinarian will advise on which formulation would work best for your pet, with most veterinary pharmacie carrying this medicine and compounding pharmacies offering custom tablets or liquid solutions with less bitter flavors if your pup dislikes its bitter flavor.

Your vet should conduct an in-depth medical history review before prescribing clindamycin to your pet, as it may interact with certain medications and cause health complications in some pets. Clindamycin can reduce levels of cyclosporine in their system and should only be taken in conjunction with neuromuscular blocking agents such as pancuronium for maximum effectiveness.


Dependent upon where their infection lies, how the medication is given and the bacteria it targets, some pets taking clindamycin may experience diarrhea as a side effect of taking this antibiotic medication. While it can be particularly distressing for dogs already dealing with stomach issues from taking antibiotics, such symptoms should generally only last temporarily and be minor side effects; your veterinarian will provide instructions to manage side effects effectively.

Clindamycin works by blocking certain proteins within susceptible bacteria cells and thus stopping their growth and multiplication. Additionally, it may interfere with key proteins produced by certain strains of bacteria, ultimately leading to their death. As a lincosamide antibiotic medication it’s used for infections of skin, bones, joints, kidneys lung mouth – as well as being an ideal replacement drug for pets that are allergic to penicillin-based medication.

Oral clindamycin medication given to dogs can lead to vomiting and bloody or watery diarrhea in some instances, particularly if given on an empty stomach. For best results, give this antibiotic with food but never exceeding what your veterinarian prescribes in terms of dosage or frequency. In case your pet experiences other gastrointestinal discomfort while on this antibiotic, your veterinarian may suggest probiotic supplements in order to restore normal gut bacteria balance.

As overdoses can have serious implications, it’s essential that you follow your veterinarian’s instructions when giving clindamycin to your pet. Your vet will explain how best to administer it with liquid or pills and what kind of food should accompany it. Dry pills should be avoided as they can get stuck in their throat and cause ulcers; alternatively you could try hiding medicine within treats in order to make the medicine more palatable for your pet.

Some veterinary clinics provide compounding medication tailored specifically to your pet’s needs by a veterinarian or licensed pharmacist, who creates it on an individual basis to meet them. Compounding may be prescribed if your pet is having difficulty swallowing pills or does not respond well to FDA-approved formulations of this medicine.

Gastrointestinal Disorders

Dogs prescribed clindamycin may experience various gastrointestinal side effects, including stomach pain and nausea. If these side effects arise, they can make your pet very uncomfortable and could indicate that the medication is no longer working effectively – consult your vet about possible symptom relief solutions.

Clindamycin comes in both pill and liquid forms and should be taken orally by your dog. To ensure maximum absorption, try giving this medicine with water or food so that the medication enters their system quickly without staying in their esophagus and leading to ulcers. Since clindamycin has an extremely bitter flavor, you may need to hide its pill among some of their favorite treats in order for them to take it without issue.

Keep in mind that this medication may lead to loss of appetite in some dogs, so make sure you pay close attention as to their reactions while on it. If they appear lethargic or are no longer eating as expected, please reach out immediately to a veterinarian for advice.

Diarrhea, whether bloody or watery in nature, is another symptom that may arise in an animal suffering from chronic conditions. When this happens, your vet may administer dehydrating agents like IV fluid bags as a dehydrating measure.

Some dogs with severe kidney or liver diseases should only receive a reduced dosage of this antibiotic due to increased liver enzymes that could pose serious risks. Furthermore, it’s essential that any dogs who have colitis, asthma or allergies that could potentially cause skin issues be administered this medication with extreme caution.

This medication is generally safe, though you should be wary of some potential side effects. Your vet should review your dog’s medical history and medications prior to prescribing this one for them; if other drugs will also be being given at the same time as this one, blood work should be conducted prior to and post administration to check for interactions that could arise from using both at once.

Injection Site Pain

Clindamycin may cause discomfort at the injection site for some dogs receiving antibiotics for serious infections like pneumonia or meningitis, particularly if given intravenously or subcutaneously. Over time, however, most dogs should adjust to it and experience less soreness at their injection site than initially anticipated; otherwise it may remain sore for several days after administration.

Veterinarians use clindamycin to treat infections caused by bacteria and protozoal organisms, including osteomyelitis. Additionally, this antibiotic may help manage wounds, dermatitis, abscesses, bite wounds, dental infections and toxoplasmosis infections that affect some cats and dogs.

Antirobe, Cleocin and Clinsol are available as liquid, capsule and tablet formulations and sold by many animal pharmacies; orally administered cat medicine can also be administered.

Clindamycin works by inhibiting the production of proteins necessary for bacteria survival. As such, it acts as a broad spectrum antibiotic effective against bacteria, protozoal organisms, viruses, and some fungi; and in addition has proven successful against some forms of malaria.

This medication should not be given to pets with severe kidney or liver diseases, colitis or allergies that cause skin problems, asthma, eczema or other inflammatory conditions, nor those pregnant or nursing pets.

Veterinary doses of an antibiotic range between 2.5-15 mg per pound of your pet’s bodyweight every 12 hours. If a wound becomes infected, or an abscessed wound or dental infection arises, dosage will likely increase significantly; your veterinarian will prescribe more intensive therapy.

When using this antibiotic, follow your veterinarian’s instructions exactly and inform him/her if your pet has any additional medical conditions or is taking medications such as vitamins or supplements – this will allow him/her to determine an accurate dosage of clindamycin for your pet. Furthermore, bloodwork should be conducted periodically on prolonged use to assess liver and kidney functions.

Lisa Thompson

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